Young and talented Han van Meegeren is a rebel in the early 1920's Amsterdam art-scene. Because he paints in the style of his idols Rembrandt and Vermeer, critics find his work old-fashioned and they call him a copycat. Just to prove a point, he produces a fake Vermeer and tries to pass it off as a real one. It works. Instead of revealing the truth and thereby embarrassing the art world, he continues to make money off of his many forgeries. Soon he is caught in a web of lies and deceit, and his life spins out of control. Then one day, high ranking Nazi Hermann Göring knocks on his door, looking for a Vermeer for his private collection...

The film is set in 1521 Antwerp, in a Europe ravaged by religious wars, and during the early years of the Reformation. It tells the story of the twelve year old, Falko Voeten – a printer’s son. When Falko’s father, Klaas Voeten, a printer of forbidden literature, is caught by the Inquisition for printing a letter written by Maarten Luther; Falko is unwittingly propelled into helping his father and into searching for the letter. Threatened by the Inquisition but aided by Marieke, a Catholic orphan girl from the underground sewers, Falko is faced with a race against time if he is to save his father from being executed for heresy.